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On this post we collate some of the Raman spectroscopy terms, along with a short description to help guide through many of the different techniques often used today in the field of Raman spectroscopy. 

In this post, read about what performance improvements can be achieved by using a 405 nm laser compared to longer wavelength lasers that are used more conventionally in Raman experiments.

There is a number of different kinds of lasers available at 785 nm. They offer different performance and cost characteristics, which means a careful selection can be important to find the best solution for a particular Raman spectroscopy set-up. In this post we summarise the available technologies around 785 nm.

Raman spectroscopy provides an intrinsic label-free contrast mechanism from the sample that is rich in biochemical content. Taking 2D information of the molecular distribution that conforms the sample is thus, very attractive to the biomedical science community. Read about how the unique combination of Raman and light sheet microscopy is helping us learn more.

The low-frequency Raman region probes the same low-energy vibrational and rotational modes of molecular structures as terahertz spectroscopy (300 GHz – 6 THz). The THz region of Raman spectra contain important structural information about the molecules or crystal lattices under investigation. In the pharmaceutical industry, for instance, this structural information can help to determine the crystallinity, and therefore solubility, of pharmaceuticals. Read more about how here.

Choosing the best illumination wavelength for a given application is not always obvious. Many system variables must be considered to optimize a Raman spectroscopy experiment, and several of them are connected to the wavelength selection.

Tip-enhanced Raman spectroscopy (TERS) is an approach that has been well recognized and relies on strongly localized enhancement of Raman scattering of laser light at the point of a near atomically sharp tip. However, not least due to the lack of sources delivering laser light tunable throughout the visible spectral range, the vast majority of TERS experiments so far has been limited to single excitation wavelengths. Read about how a CW tuanble laser can help change this!